Let think twinkies! You can open a package of twinkies and let it sit out for a long time. A long time. A long, long time. They you can eat it. Long shelf life means it does not succumb to digestion by random microbes etc in the environment. Does the twinkie then succumb to the random microbes in your gut? I think not, but what do I know.
Then there is living food. You can take milk, put a culture in it and let it grow for 10 hours. Instant pot, heating pad, whatever. Then you eat it. It is now filled with living cultures. It tastes better to me than any store bought yogurt, costs exactly the same as the same quantity of milk. With a chopped apple, cinnamon and a tiny bit of sugar it tastes better to me that most of the faux ice cream you get these days.
What is funny to me is the conversations we have about "ultra processed food" do no address this aspect of the issue. I keep wondering why.