I use pyright with a 50k LOC Django REST API codebase. I haven't really had problems. From my pyproject.toml:

django==4.2.30

djangorestframework==3.16.1

---

django-types==0.15.0

djangorestframework-types==0.8.0

pyright==1.1.390

My dj version is pretty old, but I'd assume things have only gotten better since v 4?