In what ways? I'm sure there are businesses they refuse to support (like any company) but I have a family member running a Shopify store (selling things that you couldn't over Amazon due to logistics) and Shopify
- Doesn't have any pre approval process for products. We can add and edit products instantaneously with no process involving anyone else.
- Has never appeared to care, even when "products" are things like "we agreed on a delivery method over the phone".
I'd also point out that the store owns the brand with Shopify. We could switch out the backend for a different ones and the users wouldn't really notice. You couldn't do the same with Amazon.