Everyone keeps saying that Sprint was a nuke. That is true. However, it also scored some kinetic kills during testing at Kwajalein.
https://www.youtube.com/watch?v=YZZV464z9g8
I'm pretty sure that improvements in sensing, computation, actuation, and conventional warhead design over the past 50 years could have produced a reliable hit-to-kill Sprint. And in fact, some research was done on such a vehicle, the McDonnell-Douglas HEDI.