Isn't the idea more that the large-scale political forces are what allow those supposedly "great men" to become "great" in the first place? Yes, once Napoleon was in power, a lot of the details of history were dependent on his individual decisions - but the forces that led to the French Revolution were what gave him that power in the first place. An if he had actually died of a stroke, or if Hitler had been killed in WWI, then the specifics of history would have been different, but probably not the large-scale trajectory: Post-revolutionary France would still have been there and the deep divisions, senses of injustice and reactionary and capitalist influence in post-WWI Germany that gave rise to the Nazi movement would also still have been there. And chances are, other "great men" would have emerged and captured those forces.
As such, I see the relationship more like the one between lightning strikes and wildfires: Yes, a particular wildfire might have been caused by that particular lightning strike (or careless hiker or whatever), but the reason why that particular local event could spiral into a blaze that burns down acres and acres were the larger environmental conditions, i.e. hot weather, wind and dryness. And if firefighters could take a time machine and prevent that particular cause, then it's likely another random event would trigger a slightly different but still extremely similar wildfire - so not much would have been won.