us-east-1 is a region. That means that it is 3 to 6 “availability zones” within a 100 km or so. Each of these availability zones consists of a cluster of data centers. Each cluster is perhaps 3-5 that are a few km from each other. The data centers will have tens of thousands of servers each.

So that is the mental model you should have for “how big is us-east-1”. But also, the data centers are not going to be, individually, anything like 244 acres. Best guess is that individual data centers are between 200,000 and 400,000 square feet. That is 5 to 10 acres.

Do the math above and us-east-1 may be 300 acres of floor space spread over a very large area.