The spruce and other local conifers (I live by the Bohemian Forest/Bayerischer Wald) have pollen that seems to be low allergenic by design. I know a lot of people who are allergic to birch or weed pollen, but not to spruce.
Not familiar with the biology of the matter. But I would assume there are advantages and disadvantages to the weight of the pollen in how it disperses and pollinates.