Memory corruption vulnerabilities are possible whenever a language is used that performs copies of data across buffers without in-language guards.
This vulnerability does not require knowledge of the memory layout to generate worker crashes against a system with vulnerable configurations.
The vulnerability is not the end of the world. System administrators will upgrade nginx with the security patch when it's released across most distribution paths (right now it's available only on unstable Debian for example). In the meantime sysadmins will likely remove the vulnerable directives from nginx configs.