Even though the project was meant to be educational, it gave me an idea I can't get out of my head: what if we started building ultra-optimized inference engines tailored to an exact GPU+model combination? GPUs are expensive and harder to get with each day. If you remove enough abstractions and code directly to the exact hardware/model, you can probably optimize things quite a lot (I hope). Maybe run an agent which tries to optimize inference in a loop (like autoresearch), empirically testing speed/quality.
The only problem with this is that once a model becomes outdated, you have to do it all again from scratch.