This is the beginnings of a wrapper around various windowing Apis to create a Window class https://github.com/Benvie/node-Windows/blob/master/Window.js

This is the beginnings of a windows registry library https://github.com/Benvie/node-winreg

This is an example of creating a windowless event loop in order to create a low level keyboard/mouse hook https://github.com/Benvie/node-Windows/blob/master/input.js