I used it between 20016-2023 and since we were not a python shop, I never used any other package managers. It was never an issue with CI/CD pipeline, but iterating locally was always a fight to getting molecule to pick up the right pyenv. It got better towards the end, though.

Honestly the bigger issue was testing x86 docker images on an arm mac, as molecule didn't cleanly support cross platform images and we did pull in x86 binaries for our playbooks (by the end of my time at said company, I was also directly managed by product managers who didn't care about tech debt and I couldn't deal with the otherwise desirable idea to move our compute to ARM - a rant for another day). This may also be fixed now.