Although I am in agreement, I believe it best to re-emphasize the qualifiers for such an endeavor (totally IMO):
1) A single founder must have already had an exit; 2) A single founder must be able to speak to their own weaknesses and address how to balance those to potential investors; 3) A single founder must have domain experience.
Finally, although most people anticipate a single founder as a CEO with technical skills, I believe that a better single founder is a CTO with business skills.
But I guess we'll see where I end up... ;-)