* You have a restricted shell or other way to execute a restricted set of commands or binaries, often with arbitrary parameters. You can use GTFOBins in interesting ways to read files, write files, or even execute commands and ultimately break out of your restricted context into a shell.
* Someone allowed sudo access or set the SUID bit on a GTFOBin. Using these tricks, you may be able to read or write sensitive files or execute privileged commands in a way the person configuring sudo did not know about.