I've used barman on somewhat large-ish DBs (30+ TB), and had no complaints with it. I am a DBRE, if that holds any weight.
Also, pgBackrest lets you do the majority of the backup from a physical standby, which is VERY nice for removing the load off production.
None of these seemed like issues, until we looked at pgBarman, and suddenly realized how nice that would be.
I'll take a look. Thanks!