Regarding applications/industries - after software development as an industry I see scientific research benefiting the most from agentic AI and autonomous machine reasoning. Another domain which is still not saturated would be something I call "personal guardian angel", which usually extends to whole families. Quite often people use OpenClaw for these use cases. Personally I build my own harnesses. One instance is set up as a CEO of my organization, taking care of operations, and another one, completely separate, operating over private knowledge about my family matters, schedules, medical history, etc. I predict context graph and metacognitive use cases to get rapid adoption this year.

- I've built 2 harnesses, one called Claudine - an older sister of Claude Code which now I use for teaching harness engineering, and Golem XIV, with context/knowledge graph management and self-directed metacognitive research.

- In practice rather Anthropic models if the quality of the metacognitive reasoning process and self-improvement loops are considered.