I think the gestures are cool, and in a world where everyone was really into "neat" interfaces it'd be the way to go. They score particularly high on efficiency.
But designers tend to drastically underestimate discoverabity, particularly discoverabity by novice users. Many entire software companies exist purely because the market leader's product lacks discoverabity of a feature. Twitter, in some ways, exists because blogging software doesn't make it obvious that you can use their platforms for microblogging.
If you think of usability as a funnel, with discoverabity feeding into learnability feeding into usefulness feedin into ease of use feeding into efficiency feeding into fun, discoverabity is like your home page. It's where you have the biggest drop off of engagement typically, and it's where problems can absolutely make or break you.
Offscreen and corner gestures, while useful and efficient, are often so undiscoverable that they almost exist only for power users. On the lates Build and Analyze, Marco Arment said he has to include a button to show the side navigation on The Magazine because so many people have no idea they can swipe in from the left.
Apple typically gets this better than most companies, and will use a text button instead of a gesture because they know that even if 80% of users discover the gesture, they just can't rely on it for your core interaction. Because the 20% will just walk away and tell all their friends the product is crap.
My prediction is that over-reliance on gestures and hot corners will put a serious damper on Windows 8 and Windows Phone's network effects. It's good design for power users, but it's in no way universal design and for an OS universal design is a must.