Long before even extraction/refining costs make remaining oil infeasibly expensive, supply/demand will send the price spiking to uneconomical levels as soon as oil production so much as slows down relative to growth in world-wide demand.
That's what the US increase in extraction is primarily about: trying to avoid price shocks between now and when the economy is, or can be, substantially run on natural gas and renewables as global demand outstrips supply. And even then, all we'll likely have done is smoothed the increase in price over the next 20 years.
Similarly, the increased CAFE standards are much more about lowering American dependence on oil, fleet-wide, than environmental concerns.