Midlife Sleep Irregularity Linked to Higher Risk of Major Cardiac Events

doi.org

7 points·gnabgib··4 comments

Individuals with irregular bedtimes had a 2.01-fold higher risk of MACEs compared to those with regular bedtimes (HR = 2.01, 95% CI: 1.00–4.01, p = 0.049), and those with irregular sleep midpoints had a 2.00-fold higher risk compared to those with regular midpoints (HR = 2.00, 95% CI: 1.01–3.98, p = 0.048).

So it doubles one's chance of a heart attack or stroke. Gnarly.

And not only that, people with comorbidities for major cardiac events have worse sleep (sleep apnea, etc.) Sort of a chicken-ekg situation. Nyuk nyuk.

I wonder what "irregularity" means. It seems they didn't define this clearly. Are we talking about few hours or is this a weekly night shift flip flop.

They do define it clearly in the 45 page linked PDF. They look at 7 day standard deviation of bedtime, then separate it into 3 groups where the worst one is labeled irregular.

The standard deviation of the worst groups bedtime was 108 minutes.

“For bedtime regularity, the median variability was 33 min (IQR 13) in the regular group, 59 min (IQR 15) in the fairly regular group, and 108 min (IQR 55) in the irregular group. For wake-up time regularity, the corresponding values were 41 min (IQR 19), 73 min (IQR 15), and 114 min (IQR 41), respectively. For the sleep midpoint regularity, the median variability was 33 min (IQR 13) in the regular group, 55 min (IQR 11) in the fairly regular group, and 93 min (IQR 40) in the irregular group.”

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