The argument being that someone (not the voter in this example) may have specifically wanted that sex offender registration part, but didn't feel that that one single part would be juicy enough, and so instead managed to get it tacked on to a much larger campaign.
For whatever reason it was included, however, as an individual voter, if you are for "increased punishment for human trafficking" but against that smaller part about sex offender username registration, you don't really have anything you can do other than decide "on the balance".
(To be clear, I went into this in more detail, as I think you were interpreting me to say that the sex offender registration part was the way to push through the human trafficking change: I was attempting to imply the reverse, although I think the argument stands even if the parts are just considered related to many people, as you still must decide what to do if you agree with the first half but disagree with the second half.)
As a specific example where I had to do this, I was for the changes being proposed to the California nexus tax formula that were on this same ballot, but was not certain if I agreed with having a large percentage of that new corporate income tax be earmarked specifically for clean energy (locking it away from education, infrastucture, or any number of other number of things it could be used for). However, as that part had a limited time horizon (five years), and as I felt the other change made sense, "on the balance" I decided to vote for that proposition.