Humans in space are currently still a waste of time/money, largely just a big surrender to PR, space-selfies, the attention economy, and the general emphasis on "seem not be" you see elsewhere. Please just send robots, build a base, and let us know when we can put more than ~10 freaking people up there at one time. If that fails, then at least we'll have results in robotics research that can be applicable elsewhere on Earth right now as well as help us achieve the more grand ambitions later.
House is on fire, has been for a while, fuck business as usual. I honestly think all those smart people ought to be charged with things like using their operations research to improve government generally, or with larger-scale high tech job programs. If you don't want to let NASA big-brains try to fix healthcare, we could at least let them fix the DMV. Hell, let them keep their spin-offs too, so they actually want success, and have some part of their budget that won't disappear. Basic research and fundamental science is (still) something we need, but we need to be far more strategic about it.
Food for thought: The way things are going, we can definitely look forward to a NASA that's completely transformed into an informal, but publicly funded, research/telemetry arm for billionaire asteroid-mining operations, and thus more of the "public risk, private-profits" thing while we pad margins for people who are doing fine without the help. OTOH, if NASA is running asteroid mining businesses at huge profits, then they can do whatever they want with squishy volunteers as a sideshow, and maybe we'll have enough cash left over to fund basic income.