Yes, you have a good point on the inconvenience of regular syncing...but I guess my use-case for Glacier would be for files that do not need to be regularly synced.
For example, as a photographer, I have roughly 1.5 TB in photo files. The vast majority of these I will never need to access again because the ones that I've liked, I've either stored in other drives (for example, a small drive of wedding photos for my portfolio or for recent customers) or on online services (yes, I know this is a cost in addition to the external drive, but I was using these services already, and for reasons other than just storage).
So for me, Glacier would be a place where I dump a chronological store of photos, a first-in-last-out kind of system. There's no need to regularly sync any of these photos. There may be a need to go back through certain folders years from now if I decided to compile something for a family album or something bespoke like that. And for that reason, it's necessary to have a last-resort store for these files.
So if I have 1TB of files that need to be rarely accessed and never updated, it's hard to justify spending that on Glacier (assuming I have a pretty safe external place to store this drive). At the rate that I accumulate files, it should only take me about an hour a year to backup photos. (plus the time it takes to find the hiding place for the hard drive).