Come to think of it, domain knowledge should be an LLMs strong suit as long as you can provide the right documentation, which is working pretty well already.
Right now the main issue I see with AI is that it doesn't do well with scaling. It's great for building demos and examples but you have to fix its code for real production work. But for how long?
Post-LLMs, the value of this (as differentiator) has dropped to zero. Domain knowledge (also known as business knowledge) is the obvious area to skill up on. It simply means knowledge about the area your organisation is working in. Whether it is yogurt delivery logistics, clothing manufacturing supply chain systems, etc. That's the real differentiator now. Anyone can invert a binary try in 5 minutes using an LLM. But designing a software system knowing well the domain your organisation is in is invaluable.
At the same time medicine, hardware design, good industrial, and specific domain knowledge (problems you solve in assembly or control loops) that are fundamentally proprietary and aren't well documented will continue to have value even when LLMs make solving the problems around them easier. Those might have increased leverage, at least for this round of LLMs. Now, maybe they succeed in World Models, but that is not today.
Really, I don't know what "kids these days" are going to do. I couldn't have predicted the influencer boom 15 years ago, but I also think there are geopolitical risks that are probably bigger than that shift, and "synergized" with the push to AI Everything, it doesn't look like a good time to be a learning/working human.