It feels like you're arguing in favor of narrowing our vantage as a way to preserve meaningfulness, which is totally valid to me. But it's basically using a belief (the meaning of temporary things as you put it) as comfort. My point, as was pointed out below, is that you may as well move but you also may as well stay still.
As an aside, it seems strange that Jobs is the illustrative example here, as if it's primitive that we should all want to be Him. Given the option to gain a problematic and presumably painful personal life and what I understand was a totally unnecessary early death along with creating apple and "changing" an arbitrarily tiny subset of human history, that seems like a very easy thing to decline. I take his decision to avoid treatment to reflect profound pain that I would love to avoid.