For most of my career, sticking to rule 3 made the most sense. When the CS major would be annoying and talk about big-O they usually forgot n was tiny. But then my job changed. I started working on different things. Suddenly my job started sounding more like a leetcode interview people complain about. Now n really is big and now it really does matter.
Keep in mind that Rob Pike comes from a different era when programming for 'big iron' looked a lot more like programming for an embedded microcontroller now.