I've been using the ~. shortcut for a while, but somehow escaped learning about the help menu.

Another neat thing I noticed while playing with it just now: there's an option to enter ~ twice to send a literal ~, but usually you don't have to do this when typing something like 'ls ~' in a regular session. Not only does the ~ have to be the first character on a line to start an escape sequence, but typing on a line, backspacing all the way to the start and then typing ~ also sends a literal tilde. It only triggers the escape sequence if the ~ is the chronologically first character after a newline (or first in the session), which is an unlikely thing to type into a shell in a normal session. Good choice of UI, both the character and the state machine.