The problem with these is they're also problems where there are actors profiting from the failure to fix the system - the issue isn't that we don't understand the complex nature of the domain, it's that the components of the system actively and agentically resist changes to the system. George Soros called this Reflexivity - the fact that the system responds to your manipulations means you can't treat yourself and the system as separate agents, and you can't treat the system as a purely mechanistic/passive recipient of your changes. It's maybe the biggest blind spot for people who want to apply the rules and methods of physics to social issues - the universe may be indifferent, but your neighbors are not.