There are zero reasons to assume this regime's victims, except for known tyrants like Maduro and Khameini, to be guilty at all. The regime has zero credibility when it comes to human rights. So those fishermen were most likely innocent victims and not drug smugglers.
In addition to all this, don't assume that this US attacks on Iran were because of his love and benevolence for the Iranian civilians. If it were so, he wouldn't have provoked the Iranian regime to crackdown on the protestors and kill around 30K of them. That farce was unnecessary for the liberation of Iran. Instead, he used them to create an excuse to carry out an attack that they had already planned.
So, as much as I understand the Iranians' joy in seeing the end of Khameini, I strongly suspect that this is just the beginning of another authoritarian regime over there, controlled remotely by the US regime this time, just as we see in Venezuela. Expect everything from human rights violations to mass scale plunder of their natural resources. All that we see now are just ploys to establish a worldwide neocolonial order under a very racist and xenophobic regime operating from the US. Let me remind you of the meme that this orange dictator posted that shows Canada, Venezuela and Greenland as part of the US territory. I don't see this end well for any civilians on this planet, including US citizens.