That depends on the kind of animations - typically for user interfaces, it's just moving, scaling, playing with opacity etc.. that's just updating the matrices once.
So you describe the scene graph once (this rectangle here, upload that texture there, this border there) using DOM, QML etc..., and then just update the item properties on it.
As far as the end user/application developer is concerned , this is retained mode. As far as the GPU is considered it can be redrawing the whole UI every frame..