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Similarly, a Beelink mini runs one of my Proxmox nodes and it's excellent. Literally sips power, too. I think I measured under 30w while under load. I mainly use it for my Plex instance given the N100 with QuickSync.

Does it run a mainline Linux kernel?

As of this past year (6.15+), most stuff you’d need for a regular desktop is upstreamed. Collabora has been working pretty hard on getting the chip mainlined, so it’s on a very good place compared to something like the Pi 5, which is not at all what the experience used to be in the past!

And despite their broadly similar performance, the RK3588s have significantly better power draw.

However I’m not sure of any of the rk3588 vendors that support both UEFI and have a full-size PCIe slot like the MS-R1 has.

https://github.com/edk2-porting/edk2-rk3588

RK3588 has many times better power consumption, but their performance is not at all similar.

8 Cortex-A720 vs. 4 Cortex-A76 means at least 3 times better performance for optimized programs.

Also for I/O throughput, this computer has far more fast PCIe lanes than RK3588, allowing many fast peripherals.