I used to appreciate Lisp for the enhanced effectiveness it granted to the unaided human programmer. It used to be one of the main reasons I used the language.
But a programmer+LLM is going to be far more effective in any language than an unaided programmer is in Lisp—and a programmer+LLM is going to be more effective in a popular language with a large training set, such as Java, TypeScript, Kotlin, or Rust, than in Lisp. So in a world with LLMs, the main practical reason to choose Lisp disappears.
And no, LLMs are doing more than just generating text, spewing nonsense into the void. They are solving problems. Try spending some time with Claude Opus 4.6 or ChatGPT 5.3. Give it a real problem to chew on. Watch it explain what's going on and spit out the answer.