A good starting point would be to have your design elements aligned in such a manner that they conform to the Fibonacci Golden Ratio. Here is a link to a few articles that describe Golden Ratio usage in web designing:

1. http://webdesign.about.com/od/webdesignbasics/a/aa071607.htm 2. http://www.smashingmagazine.com/2008/05/29/applying-divine-p...