Well, if you employ yourself and you could collect unemployment insurance after laying yourself off, some would consider that gaming the system.
Someone who came right out of college, made $50k for two years, is entitled to double digit weeks of unemployment benefits.
Edit: Egg on face. Just looked up the details, while I pay taxes, it seems none of these go towards unemployment insurance, unlike when you're employed, which is why the self-employed don't qualify. Lots of differences from state-to-state too, but in NY it's impossible to "participate" unless you set it up as an s-corp.