The universe does tell us something about morality. It tells us that (large-scale) existence is a requirement to have morality. That implies that the highest good are those decisions that improve the long-term survival odds of a) humanity, and b) the biosphere. I tend to think this implies we have an obligation to live sustainably on this world, protect it from the outside threats that we can (e.g. meteors, comets, super volcanoes, plagues, but not nearby neutrino jets) and even attempt to spread life beyond earth, perhaps with robotic assistance. Right now humanity's existence is quite precarious; we live in a single thin skin of biosphere that we habitually, willfully mistreat that on one tiny rock in a vast, ambivalent universe. We're a tiny phenomena, easily snuffed out on even short time-scales. It makes sense to grow out of this stage.
So yes, I think you can derive an ought from an is. But this belief is of my own invention and to my knowledge, novel. Happy to find out someone else believes this.