There are obvious good uses for it: Wikileaks in its heyday comes to mind (that is, the time when they were actually a wiki, releasing leaks while keeping their sources safe, not going out of their way to create PR nightmares for the US government). But the vast majority of other widely-defended use cases for it seem to be people using it as a license to do nasty things like jailbait/creepshots. Even VA recognized that a compromise of his identity would mean professional ruination, even as he exposed himself and his family to that risk by revealing himself to people he thought he could trust.
While Reddit definitely shouldn't start trying to "solve" the problem, clearly the use of vigilante "doxxing" as a weapon against people they don't like isn't a real solution either. Is there even a good middle ground? "Do distasteful things on peril of Gawker running a story about you"?