The same ways Vercel makes it harder to deploy Next.js sites to competitors or for self hosting.
What Vercel really did was make Next.js work well in serverless environments, which involves a lot of custom infrastructure [0]. Cloudflare wanted that same behavior on CF Workers, but Vercel never open-sourced how they do it, and that is not really their responsibility.
Next.js is not locked to Vercel. The friction shows up when trying to run it in a serverless model without building the same kind of platform Vercel has.