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If you're staying in python or another dynamic language it could probably work. Unfortunately I don't think there are a lot of native compilers that run on esp32s, though there are some[0]

[0]: https://github.com/valdanylchuk/xcc700

I have used the T-Deck with tulipcc for coding and writing, although these days I mostly use it as a calculator. I wrote a GUI text editor for it, which you can find here:

https://github.com/coolcoder613eb/notepad

I haven't done too much coding with it, but I have on occasion fixed bugs in the text editor on the T-Deck itself.

As well as micropython, there is also a port of ulisp. http://www.ulisp.com/show?4JAO