Not available for one time purchase are the AI features and templates available for the free apps (Keynote, Pages, Numbers, Freeform).
Personally, I'm glad that one time purchases are still options for the core pro suite: long term they do hold value compared to paying Adobe a subscription (or dealing with the high seas on macOS). However, I don't see things like the education bundle sticking around much longer, so purchase it sooner rather than later.
[1]: https://www.apple.com/us-edu/shop/product/bmge2z/a/pro-apps-...
[2]: https://apps.apple.com/us/app/pixelmator-pro/id1289583905