In my experience, it seems to. My astigmatism (or other eye stuff) seems to move different colours different amounts, leading to wider RGB pixels and making things like Cleartype so much worse. So people were enjoying Cleartype and I was hating the obvious colour-changes and fringes that somehow they weren't seeing. I assume some people are lucky enough to have aberrations that actually make cleartype more pleasant.

I do too. Combined with progressive lenses and I have significant chromatic aberration issues. Blue and red pixels require different focus, which is sometimes an issue when solid blues and reds are on screen in close proximity. I turn off pure blue colors in my terminal emulator, for example.