I'd just say it's a burden and a bother.
I generally view that life has no meaning out of the box. We tend to think of terms like "meaningless" as a negative thing, but I see that more as a reaction to the indoctrination of a society that insists on lives having meaning. You wouldn't say a scattering of sand on the floor had "meaning," but you also wouldn't call the scattering "meaningless" in its negative connotation.
And just as we could use our finger to arrange the sand into a message and assign it meaning, we can choose to assign a meaning to our own lives. But that's still doesn't mean it started having meaning. If it did, that would be predestination, which is absurd.
Those ends would say that suffering is a product of our own making. It is a choice. Bad things can happen to you, but your perspective on the situation creates the suffering (resistance, guilt, personalization, inability to see it as a change agent, etc.).