This assumes there are no errors anywhere in the sizes or alignments of the A4 base page or either A5. Otherwise, you'll have an A5 running over an edge of the A4 or both A5s overlapping in the middle.
If your pages are designed with margins on the assumption that errors in the paper are common, this issue disappears because the margins cover for it. But still, if I wanted to do a display of two 8.5" x 11" sheets of paper, I'd want a board that was bigger than 17" x 11".