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Isolated populations "drift" genetically, which is how species form in the first place. Discriminating against people based on those differences sucks, sure, but it's still the ground truth.

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It does suck, but the differences on which discrimination happen do not map to actual genetic variation.[0]

[0] https://bioanth.org/about/aaba-statement-on-race-racism/

Pretty sure there are genetic clustering algorithms which show that perceived race groups approximately correspond to measured race clusters. For example, random East Asians are more closely related to each other than to random West Europeans.

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