My Mercedes is absolutely terrible at this. Having owned it for a couple of years now I still have no intuition about what most of the steering wheel buttons do. On the other hand, they get cruise control right: It's a simple stalk on the steering column. Up for faster. Down for slower. Easy to find and operate without even a glance off of the road.
If there were a few carefully chosen single-purpose buttons on the steering wheel I could maybe get on board. But if there are too many or they are multifunction then it's cognitive overload.