The personas have to paper specific I believe, addressing the content and methods. I guess an LLM could do a once over of the paper or meta-analysis to determine the best discipline specific personas - but would be interesting to test that. But there are also the benefits of deep expertise and understanding a field for decades. For example, I know a set of authors who repeatedly find significant associations in a field in almost every study they do, whereas others have variable results. They also seem to ignore good studies that disagree with their hypotheses and use inferior studies that support their position in review papers - so I dont really trust their work. It would be great if an LLM could develop that kind of understanding and somehow deprecate a body of work that had inherent author or institutional biases - even though on the surface the review looks legitimate. For a meta-analysis it is often the papers that are omitted that are most telling. That means the LLM will need to redo the entire search and synthesis - yikes!