> I don’t think it’s worth doing that
OK; it's your choice to do what you think is right.
> and comparing it to scientific experiments doesn’t really apply.
Why not? I think it's a fairly apt comparison; you have a theory ("this piece of code does the following things"), and write tests to prove it.
> You can do all that without mocks as well.
OK, but mocks make it easier and cleaner - so why wouldn't I do that?
> Making the tests run faster at the expense of better tests seems counterproductive.
Smaller, more focused, cleaner tests are better in my opinion; speed is a beneficial side effect.
> Now you should think of reasons why you should not isolate.
Why? That's your argument - it's not on me to prove it for you. If you can give me some good reason why mocking out the interfaces you are not testing is a bad idea, and some better alternative, then we can have a discussion about it.