Wait until you see ImGui bindings for Python [1]. It’s immediate mode instead of retained mode like Tkinter/Qt/Wx. It might not be what you’d want if you’re shipping a thick client to customers, but for internal tooling it’s awesome.

    imgui.text(f"Counter = {counter}")
    if imgui.button("increment counter"):
        counter += 1

    _, name = imgui.input_text("Your name?", name)
    imgui.text(f"Hello {name}!")

[1] https://github.com/pthom/imgui_bundle