Kind of depends on your mac, but if it's a relatively recent apple silicon model… maybe, probably?

> Nemotron 3 Nano is a 3.2B active (3.6B with embeddings) 31.6B total parameter model.

So I don't know the exact math once you have a MoE, but 3.2b will run on most anything, 31.6b and you're looking at needing a pretty large amount of ram.