These theories are enormously successful, but they are also known to be variously incomplete, inconsistent, non-deterministic, philosophically problematic, open to multiple interpretations and only partially understood in their implications, with links between descriptions of things at different scales a particularly challenging and little understood topic. The more you learn about physics (and while I'm no physicist, I have a degree in the subject and have learned a great deal more since) the more you understand the limits of what we know.
Anybody who thinks there's no mystery to physics just doesn't know much about it. Anybody who confidently asserts as fact things like "the brain consists of protons, neutrons and electrons so it's impossible for it to do anything a computer can't do" is deducing things from their own ignorance.
You'd think it would unlock certain concepts for this class of people, but ironically, they seem unable to digest the information and update their context.