Scientists link sugar substitute sorbitol to liver disease in zebrafish | Hacker News Reader

Scientists link sugar substitute sorbitol to liver disease in zebrafish

scitechdaily.com

19 pointsmraniki8 comments

Study: https://www.science.org/doi/10.1126/scisignal.adt3549

That’s why I always feed my zebrafish real sugar

the article has very interesting examples of how individual gut biomes produce radicaly different products in different people, with some able to completly digest sorbitol, and in others is passed to the liver where it is converted to a fructose, like, compound other complicatiins are mentioned but most certainly, adding sorbitol to anything, is at best, a zero sum equation, and for many it will cause some harm. personaly, I dont argue with what nature has contrived over the countless millenia, and enjoy cooking useing whole food ingredients that are instantly recognisable as to what they are, by sight and smell. And while it IS, time consuming, I know for a fact that paying for the quality and quantity of food I make and eat, in a resturaunt, is well past my and most peoples means. The unspoken premise, here, in many discussions of health and food, chemicals, additives, pesticides,etc, is that human sensory input has no value as it is subjective, which is something I disagree with, on every level.

.. to liver disease in zebrafish.

From the study:

> depletion of the gut microbiome in adult zebrafish led to the development of steatotic liver disease in animals on standard diets

Thanks, we've in-zebrafished the title.

This is a clear improvement. I think HN should commit to in-zebrafishing one title a day so we can see if the improvements are sustainable.

Seems to have some promise:

* Whatever legitimate places AI has, in zebrafish isn't one - https://news.ycombinator.com/item?id=46120733

* ‘CEO is my blood type’: a chilling new novel nails narcissistic tech culture in zebrafish - https://news.ycombinator.com/item?id=45950784

Who in zebrafish has a right to the moon economy? Whoever gets there first - https://news.ycombinator.com/item?id=46179335

Another substitute joins unhealthy Aspartame ranks!

Ban sweeteners which are just destroying taste of everything and bring back natural sugars, focus on teaching for responsible consumption.

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