I saw the (a?) architectural model for Stata before it was built. I was with an artist, and we just walked into somewhere it had been set up for an event. (Yay for MIT culture of letting students go most places on campus.) It looked pretty crazy at the time. IIRC, there was a clear sphere embedded in the top of one of the lower roofs. My joke was that the model looked like someone had taken a paperweight, and smashed up a previously ordinary-looking building. It was crazy when construction started, and you could start to see elements of the building emerge, like, they are actually building that. (Though they left out the paperweight sphere.)
Before it was built, a designer friend, who'd worked worked in a Stata building before, mentioned the frequent complaints of Gehry buildings, such as people in triangular offices, or with slanting walls, that couldn't fit a desk.
Years later, I was surprised and deligted to end up working in Stata. My office was pretty generic rectangular and functional, with big windows that opened. No complaints about the office, except the HVAC couldn't win against the early GPU compute my officemate was doing. Space in the building was in demand by everyone, yet there were large areas of dead space. I wondered whether some of the conspicuously unused space was because they could've figured out how to adapt it, but was being banked consciously, so that space could be made for PIs who arrived later.
Stewart Brand criticized IM Pei's building for the original Media Lab (E15), as not being malleable like the "temporary" Building 20, and maybe some of the same criticism applied. Though Stata, coincidentally built partly on the site of Building 20 that was razed for it, did incorporate plywood elements in the interior, I think as a nod to Building 20. This included large plywood tables that were moved around as needed for different purposes in the open ares outside the elevator on my floor (G10?), multiple times a day.
The strange bathroom placement, and the ones that used visibly dirty ("green") water to flush, weren't a practical problem, but multiple times were awkward to explain to visitors. I liked the big single-person bathrooms on the office floors, and they were luxurious for students and professors doing all-nighters to get in a discreet paper towel bath, compared to the indignity of trying to do it in a toilet stall.
One thing I liked about the larger building design was the main street ground floor, adding cafe and various random seating, which was a big improvement over the Infinite Corridor.