A good friend of mine just flew down to Santiago for Startup Chile. He's definitely enjoying it, but before he left he was concerned that getting out of the US entrepreneurship scene might make it harder to reach US consumers and get relationships with investors. On the flipside, S.C. seems focused on creating an international community of entrepreneurs - I'm told there's teams from 33 countries.
It'll be interesting to see how many of these teams will end up in YC.